منابع مشابه
Rickettsia-macrophage interactions: host cell responses to Rickettsia akari and Rickettsia typhi.
The existence of intracellular rickettsiae requires entry, survival, and replication in the eukaryotic host cells and exit to initiate new infection. While endothelial cells are the preferred target cells for most pathogenic rickettsiae, infection of monocytes/macrophages may also contribute to the establishment of rickettsial infection and resulting pathogenesis. We initiated studies to charac...
متن کاملIsolation of Rickettsia akari from eschars of patients with rickettsialpox.
Rickettsialpox is a cosmopolitan, mite-borne, spotted fever rickettsiosis caused by Rickettsia akari. The disease is characterized by a primary eschar, fever, and a papulovesicular rash. Rickettsialpox was first identified in New York City in 1946 and the preponderance of recognized cases in the United States continues to originate from this large metropolitan center. The most recently isolated...
متن کاملMolecular typing of isolates of Rickettsia rickettsii by use of DNA sequencing of variable intergenic regions.
Rickettsia rickettsii, the causative agent of Rocky Mountain spotted fever, is found throughout the Americas, where it is associated with different animal reservoirs and tick vectors. No molecular typing system currently exists to allow for the robust differentiation of isolates of R. rickettsii. Analysis of eight completed genome sequences of rickettsial species revealed a high degree of seque...
متن کاملDetection of Rickettsia rickettsii, Rickettsia parkeri, and Rickettsia akari in skin biopsy specimens using a multiplex real-time polymerase chain reaction assay.
BACKGROUND Rickettsia rickettsii, Rickettsia parkeri, and Rickettsia akari are the most common causes of spotted fever group rickettsioses indigenous to the United States. Infected patients characteristically present with a maculopapular rash, often accompanied by an inoculation eschar. Skin biopsy specimens are often obtained from these lesions for diagnostic evaluation. However, a species-spe...
متن کاملSerological typing of spotted fever group Rickettsia isolates from Zimbabwe.
Eight rickettsialike organisms were isolated in tissue culture from ticks of dogs and cattle from various areas of Zimbabwe. These isolates and a reference strain, Rickettsia conorii Simko, were tested by microimmunofluorescence against homologous and heterologous antisera raised in mice. From the titers obtained by this method, specificity differences (SPDs) were calculated between each of the...
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ژورنال
عنوان ژورنال: Russian Journal of Infection and Immunity
سال: 2020
ISSN: 2313-7398,2220-7619
DOI: 10.15789/2220-7619-mto-1295